| Date | Time | Description | Venue |
|---|---|---|---|
| Saturday, 27 March 2010 | 4:30PM | Gold Coast - 12 v Sunshine Coast - 52 | Albert Park |
| Saturday, 10 April 2010 | 3:00PM | Easts - 43 v Sunnybank - 30 | Bottomley Park |
| Saturday, 10 April 2010 | 3:00PM | Sunshine Coast - 33 v Brothers - 20 | Stockland Park |
| Saturday, 10 April 2010 | 3:00PM | University - 26 v Gold Coast - 29 | St Lucia |
| Saturday, 10 April 2010 | 3:00PM | Wests - 8 v Norths - 55 | Sylvan Road |
| Saturday, 10 April 2010 | 3:15PM | Souths - 26 v GPS - 29 | Chipsy Wood Oval |
| Saturday, 17 April 2010 | 3:00PM | Norths - 27 v Souths - 36 | Hugh Courtney Oval |
| Saturday, 17 April 2010 | 3:00PM | Gold Coast - 29 v Easts - 29 | Albert Park |
| Saturday, 17 April 2010 | 3:00PM | Sunnybank - 37 v Wests - 14 | Oldmac Oval |
| Saturday, 17 April 2010 | 3:00PM | University - 25 v Sunshine Coast - 6 | St Lucia |
| Saturday, 17 April 2010 | 3:10PM | GPS - 38 v Brothers - 29 | Yoku Road |
| Saturday, 24 April 2010 | 3:00PM | Brothers - 12 v University - 16 | Crosby Park |
| Saturday, 24 April 2010 | 3:00PM | Norths - 37 v GPS - 31 | Hugh Courtney Oval |
| Saturday, 24 April 2010 | 3:00PM | Sunshine Coast - 20 v Easts - 19 | Stockland Park |
| Saturday, 24 April 2010 | 3:00PM | Wests - 10 v Gold Coast - 29 | Sylvan Road |
| Saturday, 24 April 2010 | 3:15PM | Souths - 17 v Sunnybank - 36 | Chipsy Wood Oval |
| Saturday, 1 May 2010 | 3:00PM | Easts - 17 v Brothers - 15 | Bottomley Park |
| Saturday, 1 May 2010 | 3:00PM | Wests - 31 v Sunshine Coast - 29 | Sylvan Road |
| Saturday, 1 May 2010 | 3:10PM | GPS - 14 v University - 37 | Yoku Road |
| Saturday, 1 May 2010 | 4:30PM | Gold Coast - 22 v Souths - 24 | Albert Park |
| Saturday, 1 May 2010 | 4:30PM | Sunnybank - 24 v Norths - 13 | Oldmac Oval |
| Saturday, 8 May 2010 | 3:00PM | Brothers - 37 v Wests - 12 | Crosby Park |
| Saturday, 8 May 2010 | 3:00PM | Norths - 43 v Gold Coast - 23 | Hugh Courtney Oval |
| Saturday, 8 May 2010 | 3:00PM | Sunshine Coast - 18 v Souths - 17 | Stockland Park |
| Saturday, 8 May 2010 | 3:00PM | University - 24 v Easts - 14 | St Lucia |
| Saturday, 8 May 2010 | 4:30PM | Sunnybank - 46 v GPS - 21 | Oldmac Oval |
| Friday, 14 May 2010 | 8:15PM | Gold Coast - 24 v Sunnybank - 17 | Albert Park |
| Saturday, 15 May 2010 | 3:00PM | Norths - 24 v Sunshine Coast - 22 | Hugh Courtney Oval |
| Saturday, 15 May 2010 | 3:00PM | Wests - 24 v University - 42 | Sylvan Road |
| Saturday, 15 May 2010 | 3:10PM | GPS - 5 v Easts - 22 | Yoku Road |
| Saturday, 15 May 2010 | 3:15PM | Souths - 12 v Brothers - 41 | Chipsy Wood Oval |
| Saturday, 22 May 2010 | 3:00PM | Brothers - 29 v Norths - 17 | Crosby Park |
| Saturday, 22 May 2010 | 3:00PM | Easts - 38 v Wests - 28 | Bottomley Park |
| Saturday, 22 May 2010 | 3:00PM | Sunshine Coast - 43 v Sunnybank - 46 | Stockland Park |
| Saturday, 22 May 2010 | 3:00PM | University - 30 v Souths - 17 | St Lucia |
| Saturday, 22 May 2010 | 4:30PM | Gold Coast - 34 v GPS - 15 | Albert Park |
| Saturday, 29 May 2010 | 3:00PM | Norths - 32 v University - 49 | Hugh Courtney Oval |
| Saturday, 29 May 2010 | 3:10PM | GPS - 40 v Wests - 20 | Yoku Road |
| Saturday, 29 May 2010 | 3:15PM | Souths - 10 v Easts - 3 | Chipsy Wood Oval |
| Saturday, 29 May 2010 | 8:00PM | Sunnybank - 16 v Brothers - 21 | Oldmac Oval |
| Saturday, 5 June 2010 | 3:00PM | Brothers - 54 v Gold Coast - 16 | Crosby Park |
| Saturday, 5 June 2010 | 3:00PM | Norths - 5 v Easts - 34 | Hugh Courtney Oval |
| Saturday, 5 June 2010 | 3:00PM | Sunshine Coast - 27 v GPS - 12 | Stockland Park |
| Saturday, 5 June 2010 | 3:00PM | University - 37 v Sunnybank - 37 | St Lucia |
| Saturday, 5 June 2010 | 3:00PM | Wests - 16 v Souths - 27 | Sylvan Road |
| Saturday, 19 June 2010 | 3:00PM | Brothers - 37 v Sunshine Coast - 17 | Crosby Park |
| Saturday, 19 June 2010 | 3:00PM | Norths - 20 v Wests - 21 | Hugh Courtney Oval |
| Saturday, 19 June 2010 | 3:10PM | GPS - 10 v Souths - 27 | Yoku Road |
| Saturday, 19 June 2010 | 4:30PM | Gold Coast - 25 v University - 27 | Albert Park |
| Saturday, 19 June 2010 | 4:30PM | Sunnybank - 50 v Easts - 18 | Oldmac Oval |
| Saturday, 26 June 2010 | 3:00PM | Brothers - 15 v GPS - 21 | Crosby Park |
| Saturday, 26 June 2010 | 3:00PM | Easts - 35 v Gold Coast - 17 | Bottomley Park |
| Saturday, 26 June 2010 | 3:00PM | Sunshine Coast - 10 v University - 25 | Stockland Park |
| Saturday, 26 June 2010 | 3:00PM | Wests - 34 v Sunnybank - 49 | Sylvan Road |
| Saturday, 26 June 2010 | 3:15PM | Souths - 32 v Norths - 28 | Chipsy Wood Oval |
| Saturday, 3 July 2010 | 3:00PM | Easts - 15 v Sunshine Coast - 25 | Bottomley Park |
| Saturday, 3 July 2010 | 3:00PM | University - 30 v Brothers - 29 | St Lucia |
| Saturday, 3 July 2010 | 3:10PM | GPS - 33 v Norths - 10 | Yoku Road |
| Saturday, 3 July 2010 | 4:30PM | Gold Coast - 21 v Wests - 36 | Albert Park |
| Saturday, 3 July 2010 | 4:30PM | Sunnybank - 29 v Souths - 27 | Oldmac Oval |
| Saturday, 10 July 2010 | 3:00PM | Brothers - 18 v Easts - 23 | Crosby Park |
| Saturday, 10 July 2010 | 3:00PM | Norths - 29 v Sunnybank - 39 | Hugh Courtney Oval |
| Saturday, 10 July 2010 | 3:00PM | Sunshine Coast - 76 v Wests - 5 | Stockland Park |
| Saturday, 10 July 2010 | 3:00PM | University - 55 v GPS - 32 | St Lucia |
| Saturday, 10 July 2010 | 3:15PM | Souths - 31 v Gold Coast - 28 | Chipsy Wood Oval |
| Saturday, 17 July 2010 | 3:00PM | Easts - 15 v University - 39 | Bottomley Park |
| Saturday, 17 July 2010 | 3:00PM | Wests - 10 v Brothers - 32 | Sylvan Road |
| Saturday, 17 July 2010 | 3:10PM | GPS - 24 v Sunnybank - 22 | Yoku Road |
| Saturday, 17 July 2010 | 3:15PM | Souths - 25 v Sunshine Coast - 10 | Chipsy Wood Oval |
| Saturday, 17 July 2010 | 4:30PM | Gold Coast - 20 v Norths - 18 | Albert Park |
| Saturday, 24 July 2010 | 2:30PM | Sunnybank - 49 v Gold Coast - 27 | Oldmac Oval |
| Saturday, 24 July 2010 | 3:00PM | Brothers - 19 v Souths - 18 | Crosby Park |
| Saturday, 24 July 2010 | 3:00PM | Easts - 23 v GPS - 39 | Bottomley Park |
| Saturday, 24 July 2010 | 3:00PM | Sunshine Coast - 33 v Norths - 15 | Stockland Park |
| Saturday, 24 July 2010 | 3:00PM | University - 38 v Wests - 24 | St Lucia |
| Saturday, 31 July 2010 | 3:00PM | Norths - 26 v Brothers - 52 | Hugh Courtney Oval |
| Saturday, 31 July 2010 | 3:00PM | Wests - 11 v Easts - 33 | Sylvan Road |
| Saturday, 31 July 2010 | 3:10PM | GPS - 52 v Gold Coast - 13 | Yoku Road |
| Saturday, 31 July 2010 | 3:30PM | Souths - 17 v University - 48 | Chipsy Wood Oval |
| Saturday, 31 July 2010 | 4:30PM | Sunnybank - 22 v Sunshine Coast - 45 | Oldmac Oval |
| Saturday, 7 August 2010 | 3:00PM | Brothers - 33 v Sunnybank - 22 | Crosby Park |
| Saturday, 7 August 2010 | 3:00PM | Easts - 60 v Souths - 19 | Bottomley Park |
| Saturday, 7 August 2010 | 3:00PM | Sunshine Coast - 10 v Gold Coast - 17 | Stockland Park |
| Saturday, 7 August 2010 | 3:00PM | University - 85 v Norths - 10 | St Lucia |
| Saturday, 7 August 2010 | 3:00PM | Wests - 27 v GPS - 39 | Sylvan Road |
| Saturday, 14 August 2010 | 2:30PM | Gold Coast - 27 v Brothers - 31 | Albert Park |
| Saturday, 14 August 2010 | 3:00PM | Easts - 59 v Norths - 19 | Bottomley Park |
| Saturday, 14 August 2010 | 3:10PM | GPS - 12 v Sunshine Coast - 31 | Yoku Road |
| Saturday, 14 August 2010 | 3:15PM | Souths - 31 v Wests - 20 | Chipsy Wood Oval |
| Saturday, 14 August 2010 | 4:30PM | Sunnybank - 12 v University - 31 | Oldmac Oval |
| Sunday, 22 August 2010 | 3:00PM | Brothers - 27 v Sunshine Coast - 37 | Ballymore |
| Sunday, 22 August 2010 | 5:30PM | University - 42 v Sunnybank - 17 | Ballymore |
| Sunday, 29 August 2010 | 3:00PM | Sunnybank - 15 v Sunshine Coast - 20 | Ballymore |
| Sunday, 5 September 2010 | 3:00PM | University v Sunshine Coast | Ballymore |
